Malcolm Long

Hi Ray,

DMF is currently listed on the FARA research pipeline spreadsheet

https://curefa.org/pipeline?utm_source=FA&utm_campaign=6a109b620c-RSS_EMAIL_CAMPAIGN&utm_medium=email&utm_term=0_ae7feab64b-6a109b620c-71573145

as under test, along with other items.

Great to hear it has had a positive result for others but IMO frustrating that…[Read more]

Having seen how the selection was done for participants in the trial, it required someone of paralympic standard recumbant cycling ability with corresponding breathing and endurance. Whilst being hopeful and grateful for any company pursuing a treatment I do wonder how effective it will be for the vast majority that couldn’t achieve the lofty…[Read more]

My daughter failed to get onto the trial as she couldn’t pedal a recumbent bike to exhaustion. My concern is the trial is being based on the equivalent of ‘paralympic’ performance and may be skewing results. Hopefully not and the reports and good effects will apply to everyone whatever their FA status.

Hi All,
Just registered today and have been following progress on etravirine as well as Diazoxide. Both these have been picked up for research:

• Diazoxide (Carlo Marobbio, Bari, Italy) – mitochondrial K channel activator that
increases frataxin expression
• Dimethyl fumarate (DMF) and Resveratrol (Gino Cortopassi, UC Davis) – to
increase frata…[Read more]