How does Skyclarys help with FA?

Friedreich’s ataxia (FA) is characterized by dysfunction of mitochondria, which are the energy production centers in cells, chronic inflammation, and oxidative stress, a type of cell damage marked by overproduction of toxic reactive oxygen species that outweighs the body’s antioxidant defenses. Skyclarys is intended to activate NrF2, which stands for nuclear factor erythroid 2-related factor 2, a type of protein called a transcription factor whose signaling is impaired in people with FA. NrF2 activates genes that promote mitochondrial function, boost antioxidant responses, and prevent inflammation.