Preventing Frataxin Degradation May Be Strategy to Manage Friedreich’s Ataxia

Researchers may have found a new therapeutic target for the management of Friedreich’s ataxia. A study, “E3 Ligase RNF126 Directly Ubiquitinates Frataxin, Promoting Its Degradation: Identification Of A Potential Therapeutic Target For Friedreich Ataxia,” was published in the journal Cell Reports. Friedrich’s ataxia is characterized by reduced expression…