Interferon gamma helps protect cells from damage in disease model

Treatment with interferon gamma (IFN-gamma), an immune signaling molecule, helped to protect against damage in a cellular model of Friedreich’s ataxia (FA), a study reports. Although IFN-gamma failed to show clear benefits in clinical trials, these new findings “could help in the design of better therapeutic schedules and shed…

Reactivating Nrf2 Pathway Restores Nerve Cell Development in FA, Mouse Study Suggests

Reactivativation of the Nrf2 pathway, which is impaired in the nerve cells — or neurons — of patients with Friedreich’s ataxia (FA), leads to the re-establishment of proper neuron development and maturation, a mouse study shows. The study, “Nrf2 Induction Re-establishes a Proper Neuronal Differentiation Program in Friedreich’s…