Altered connections between the cerebellum, a brain region important for coordinating voluntary movements, and the cerebral cortex, involved in higher-level…
Articles by Steve Bryson, PhD
Abnormalities found in sensory nerve cells — cells that detect body position and movement — derived from people with…
Researchers have developed and characterized mouse models of Friedreich’s ataxia (FA) carrying a rare disease-causing mutation, a study reports.
Nerve and heart muscle cells derived from a man with Friedreich’s ataxia (FA) showed differences in the activity of…
The investigational therapy DT-216 safely worked to more than double the activity of the FXN gene — involved in energy…
Repeat use of G-CSF stem cell therapy, an approved medicine, was safe in adults with Friedreich’s ataxia and associated with…
Levels of the protein frataxin, which are abnormally low in people with Friedreich’s ataxia (FA), are further reduced by…
Children and adolescents with Friedreich’s ataxia (FA) who have an enlarged heart were found to have a high prevalence…
Increased sodium levels were found in regions of the brain commonly affected by Friedreich ataxia (FA) — the cerebellum…
Compounds that blocked the activity of histone deacetylases — enzymes that suppress gene activity — increased the activity of the…