Although the basis of Friedreich’s ataxia lies in a genome-wide mutation in the frataxin gene that encodes the frataxin protein,…
Articles by Maureen Newman
A screen of molecules known as short-hairpin-loop-RNA (shRNA) revealed that certain features of Friedreich’s ataxia can be relieved through two…
Often times, researchers focus on cells from the brain or the heart when studying Friedreich’s ataxia. A new study from…
A remarkable new tool in the world of genetic biology is being applied to study Friedreich’s ataxia. TALEN and CRISPR…
Maintaining iron balance in the mitochondria is of great importance to cell health and is a prominent area of study…
Patients with Friedreich’s ataxia are at a high risk for developing hypertrophic cardiomyopathy, where the walls…
Rating scales used to succinctly describe the severity of Friedreich’s ataxia and the impact on patients’ quality of life have…
Patients with Friedreich’s ataxia have genetic mutations that lead to frataxin protein deficiency, but when their cells are treated in…
A long string of DNA repeats are the molecular basis for Friedreich’s ataxia. The beginning of the first intron of…
It is well known that a DNA mutation causes Friedreich’s ataxia by reducing the production of frataxin protein. Patients with…