In Friedreich’s ataxia (FA), a subset of patients develops severe thickening of the heart muscle as the heart shifts…
Articles by Margarida Maia, PhD
A combination of insulin, diabetes medications, and supplements that help cells produce energy lowered blood sugar and eased neurological symptoms…
Children with Friedreich’s ataxia are often underweight and short for their age, while adult patients are frequently overweight, so…
Adolescents with Friedreich’s ataxia (FA) are now being dosed with nomlabofusp as part of a placebo-controlled Phase 1…
Note: This story was updated Dec. 19, 2024, to clarify that the BOLD study does include measures of efficacy. Since…
Male mouse models of Friedreich’s ataxia (FA) in a study showed worse heart function than females, with weaker heart…
A recent mouse model of Friedreich’s ataxia (FA), called YG8-800, better mimics the disease’s symptoms and mechanisms in people…
A brain pathway that connects the cerebellum to the motor cortex, helping coordinate and control movement by sending important signals…
Diazoxide, a medication used to treat high blood pressure, protected cells — isolated from a person with Friedreich’s ataxia…
The use of high-resolution ultrasound in people with Friedreich’s ataxia revealed nerve changes in the armpits and arms that…