Normalizing the cardiac levels of frataxin via gene therapy or an alternative strategy could be an effective treatment for cardiac…
Articles by José Lopes, PhD
Biomarkers for Friedreich’s ataxia (FA) may come from measurements of frataxin (FXN) levels in red blood cells and energy…
Despite some benefits seen in clinical measures like cardiac health and reports by Friedreich’s ataxia (FA) patients of lesser…
Adding a molecule that specifically binds iron in mitochondria to sun creams could help protect the skin cells of…
A 12-week treatment with the investigational therapy omaveloxolone improved neurological function, and was safe and well-tolerated by Friedreich’s…
Increasing the amount of a protein called GRP75 repairs the characteristic Friedreich’s ataxia (FA) frataxin deficiency and mitochondrial alterations, according…
A gene therapy approach to increase the amount of the critical frataxin protein shows that correcting only half of the…
Central nervous system (CNS) damage in Friedreich’s ataxia (FA) starts in the spinal cord and specific brain areas in…
Pharmacological screening in a fly cardiac model of Friedreich’s ataxia (FA) identified 11 potentially protective compounds. The two most…
A new case report describes a 7-year-old boy with Friedreich’s ataxia (FA) who has a particularly early age of…