Increased thickness of the lower left chamber of the heart — the left ventricle — is one of the most…
Articles by Iqra Mumal, MSc
Reactivativation of the Nrf2 pathway, which is impaired in the nerve cells — or neurons — of patients with…
Iron chelation therapy using deferiprone, while helping heart function, does not seem to improve neurological symptoms in Friedreich’s ataxia patients,…
Vitamin E can be used to help restore the irregular balance of calcium that contributes to mitochondrial dysfunction in neutron…
Diabetes mellitus in Friedreich’s ataxia (FA) patients can be well-controlled through the use of individualized treatment regimens with insulin or…
People with Friedreich’s ataxia (FA) in South Brazil exhibited clinical symptoms similar to patients in Europe, although FA has…
Endoplasmic reticulum stress due to loss of frataxin protein plays a major role in the development of Friedreich’s ataxia and…
Inhibitors of p38 — a protein involved in regulating cell growth — show potential for use as therapeutic agents in…
Researchers modified two new classes of drugs, known as duplex RNAs and antisense oligonucleotides, targeted against the Frataxin (FXN) gene,…
Friedreich’s ataxia patients have a specific personality and neuropsychological profile that is characterized by very mild cognitive impairment, a…