News

Researchers found a 50-year-old hypertension therapy can enhance the amount of frataxin protein in cells from patients with Friedreich’s ataxia and mouse models of the disease. The finding was reported in the study, “Effect of Diazoxide on Friedreich Ataxia Models,” published in the journal Human…

Patients with Friedreich’s ataxia have impaired emotion recognition that may be secondary to neuropsychological impairment, according to a study published in the journal The Cerebellum. Expressing and reading emotions are essential social skills necessary for developing relationships, as well as for showing your own feelings. To a great…

The Friedreich’s Ataxia Research Alliance (FARA) and the University of California Los Angeles (UCLA) have joined forces to sponsor a Friedreich’s ataxia (FA) patient symposium in Torrance, California, on Feb. 23. The symposium will be an educational event for people living with FA, including patients and families.

The production and function of mitochondria — cellular power plants that convert nutrients to energy — is impaired in the cerebellum of the brain in early stages of a Friedreich’s ataxia mouse model, researchers at Children’s Hospital of Philadelphia report. The findings support the idea that the cerebellar disease in…

In patients with Friedreich’s ataxia, the severity of the mutation in the frataxin gene may become worse over time, according to a study published in the journal PLOS ONE. This insight has an impact on the understanding of the timing of symptom onset, and is crucial for the…

UCLA scientists have found that many early symptoms of Friedreich’s ataxia (FA) can be reversed, according to research they conducted in a new mouse model of the disease. Their study, titled “Inducible and reversible phenotypes in a novel mouse model of Friedreich’s Ataxia,” was published in the journal…

An attorney in Sioux Falls, South Dakota, has taken up the challenge to raise $75,000 before Christmas to fund a Friedreich’s ataxia (FA) study project at Sanford Research, after his daughter was diagnosed with the neuromuscular condition. Brendtro started a crowdfunding campaign, The Finish Line Fund, to fund the…

Researchers have identified a new compound, CT51, that can potentially protect neurons from damage in severe neurodegenerative diseases, such as Friedreich’s ataxia. It can also be used to detect iron inside cells, which could be useful for monitoring these diseases. The study, “Development of an iron-selective antioxidant probe…

Increased levels of six small RNA molecules, or microRNAs, in the blood could be a specific genetic marker for Friedreich’s ataxia features and progression, researchers have found. The study was titled “Differentially Regulated Cell-Free MicroRNAs in the Plasma of Friedreich’s Ataxia Patients and Their Association with…

Researchers at Tufts University have developed a new, more powerful method of analyzing DNA sequencing to better identify and understand complex genomic rearrangements (CGRs), which are involved in many genetic disorders and cancers. CGRs can occur in diseases where expansion of repetitive DNA sequences is a core feature, such…